ПРИМЕНЕНИЕ БАКТЕРИЦИДНОГО РЕЦИРКУЛЯТОРА REFLASH 60 ДОПОЛНИТЕЛЬНО К СТАНДАРТНОЙ ТЕРАПИИ ПРИ ТЯЖЕЛОЙ ПНЕВМОНИИ

Аннотация

Pathologies of the respiratory system in children occupy first place, both in terms of overall morbidity and mortality. Research shows that among the etiological factors of pneumonia, various bacterial and viral agents have been identified, the significance of which is not fully understood, but these cases are characterized by mixed results, lack of complete data and insufficient coverage in the literature. Severe pneumonia is pneumonia characterized by severe respiratory failure (RF) and/or signs of sepsis and multiple organ dysfunction. Today, the problem of severe pneumonia is relevant, due to the high mortality of the disease, the presence of a wide range of poly- and multi- resistant strains of microorganisms Thus, at present, the study of severe pneumonia in children has not been sufficiently studied, and the issue of using modern methods of preventing infection remains insufficiently addressed. In this regard, issues related to establishing the degree of influence of modifiable and non-modifiable factors on the development and course of severe pneumonia in children require further study; it is necessary to search for new methods for predicting the course and outcome, develop and implement new methods of treatment and prevention of the disease, which determined the relevance of our research. Key words: children, approaches, severe pneumonia, bactericidal recirculator reflash-60. ПРИМЕНЕНИЕ БАКТЕРИЦИДНОГО РЕЦИРКУЛЯТОРА REFLASH 60 ДОПОЛНИТЕЛЬНО К СТАНДАРТНОЙ ТЕРАПИИ ПРИ ТЯЖЕЛОЙ ПНЕВМОНИИ Аннотация. Патологии органов дыхания у детей занимают первое место как по общей заболеваемости, так и по смертности. Исследования показывают, что среди этиологических факторов пневмонии выявлены различные бактериальные и вирусные 440 агенты, значение которых до конца не изучено, однако эти случаи характеризуются неоднозначными результатами, отсутствием полных данных и недостаточным освещением в литературе. Тяжелая пневмония – это пневмония, характеризующаяся тяжелой дыхательной недостаточностью (ТД) и/или признаками сепсиса и полиорганной дисфункции. На сегодняшний день проблема тяжелых пневмоний актуальна в связи с высокой летальностью заболевания, наличием широкого спектра поли- и полирезистентных штаммов микроорганизмов. Таким образом, в настоящее время изучение тяжелых пневмоний у детей недостаточно изучено, а вопрос использования современных методов профилактики инфекции остается недостаточно решенным. В связи с этим вопросы, связанные с установлением степени влияния модифицируемых и немодифицируемых факторов на развитие и течение тяжелой пневмонии у детей, требуют дальнейшего изучения; необходим поиск новых методов прогнозирования течения и исхода, разработка и внедрение новых методов лечения и профилактики заболевания, что и определило актуальность наших исследований. Ключевые слова: дети, подходы, тяжелая пневмония, бактерицидный рециркулятор Рефлеш-60. Relevance. Respiratory diseases in children are one of the important problems of pediatrics and pediatric pulmonology. Despite the advances made in diagnosis and treatment, respiratory diseases still occupy one of the first places among the diseases of children and adolescents. [1,2,7]. The growing trend of respiratory pathology in children and the possibility of a high risk of relapse of severe pneumonia determine the relevance of studying the factors and mechanisms of the formation of pneumonia in children. Currently, the relevance of works devoted to the significance of markers that determine the course of the disease and the effectiveness of antibacterial therapy remains. Data are provided on the prognostic capabilities of virological examination of sputum, respiratory smear by polymerase chain reaction, determination of the degree of air pollution, study of indicators of the blood coagulation system, determination of the level of inflammatory markers in children, as the most informative laboratory criteria for diseases and the need for their timely determination. Determining the level of indicators of the blood coagulation system allows you to reduce the duration of ABT by 1.5-2 times, the length of hospital treatment, reduce the frequency of adverse drug manifestations, be one of the indicators of a complicated outcome of the disease, 441 and help reduce the development of bacterial resistance in children [10]. Inflammation, which is the main component of the pathogenetic component of the formation of clinical signs of respiratory tract damage in atypical pneumonia, and the severity of the condition of patients with reduced immunity in the acute period of the disease force us to look for new methods of treatment, diagnosis and prevention [3,5,9]. Today, one of the methods of prevention and treatment is a bactericidal recirculator - a device used to disinfect indoor air in the presence of people, purifying the air from viruses, bacteria, microbes and allergens. In patients during whose treatment a bactericidal recirculator was used, the body's protective pro