КОМОРБИДНОЕ ТЕЧЕНИЕ ПОДАГРЫ И МЕТАБОЛИЧЕСКОГО СИНДРОМА

Аннотация

In 49 patients (mean age - 50.6 ± 1.6 years, duration of disease - 9.4 ± 1.7 years) male gout were investigated anthropometric data, lipid profile, depending on the extent of the clinical and laboratory parameters. It has been established that the basic 3 clinical factors of the metabolic syndrome - obesity, hypertension, diabetes mellitus occurs in 49.3% of patients with gout. Dislipedemiya, hypercholesterolemia and increase in low density lipoprotein and very low density detected in 60,0-67,3% cases. In patients with urolithiasis frequency, severity of the violation rate of lower limb function, the number of affected joints, the number of subcutaneous tophi, arthritis incidence in the last year, the duration of the latest exacerbation and severity of gout own index higher than that of patients without metabolic syndrome. The degree of hyperuricemia and duration of the disease have a direct correlation with the degree of increase of total lipids and cholesterol in the blood serum.