EMERGENT CMV SEROCONVERSION WITH HIGH AVIDITY IN A PRIMIPAROUS WOMAN DURING EARLY PREGNANCY: A CASE STUDY

Аннотация

This case study presents a rare instance of cytomegalovirus (CMV) seroconversion in a primiparous woman during her first trimester of pregnancy, accompanied by a significant increase in CMV-specific antibody avidity. The emergence of CMV seropositivity in pregnancy raises concerns due to potential vertical transmission risks. However, the intriguing aspect of this case lies in the unusually high avidity of the CMV-specific antibodies developed post-seroconversion. This phenomenon suggests a previous immune priming event or cross-reactive responses. The case underscores the complexity of CMV infections during pregnancy and the need for careful monitoring and research to comprehend the implications of heightened antibody avidity in the context of maternal-fetal health. KEYWORDS CMV seroconversion, avidity, pregnancy, vertical transmission, primiparous woman, cytomegalovirus, antibody response, immune priming, cross-reactivity, maternal-fetal health.