Изменения активности нейтрофилов крови при экспериментальном бактериально-иммунном пародонтите и их коррекция флавонолом

Аннотация

The purpose of the study was to evaluate the activity of neutrophils in the blood under the condition of the experimental bacterial-immune periodontitis and to clarify the effect of flavonol quercetin on its parameters. The article presents the results of research on the indices of the spontaneous and activated test with nitrosin tetrazolium on the 14th day of the experimental bacterial-immune periodontitis and after correction with quercetin (in the same period of the experiment). In this case, data on the nature of changes in neutrophilic activity in the process of formation of inflammatory focus in the periodontal complex are given. The use of flavonol quercetin, which, acting on the immune processes, limited the inflammatory response in the periodontal tissues and led to a decrease in neutrophil activity relative to the rates of animals that did not receive the drug. As a result of the use of quercetin, the activity of neutrophils approached the values of the control group.