HEPATIC ENCEPHALOPATHY CAUSED BY ENDOGENOUS INTOXICATION IN PATIENTS WITH DIABETES MELLITUS COMPLICATED BY PURULENT-SEPTIC LESIONS OF SOFT TISSUES, WAYS OF THEIR CORRECTION

Аннотация

Objective: to study hepatic encephalopathy caused by endogenous intoxication in patients with diabetes mellitus (DM) complicated by necrotic soft tissue lesion (PNSTL) and ways of their correction. Materials and methods: 58 patients with diabetes mellitus complicated by purulent-necrotic soft tissue lesion and the effect of endotoxicosis on the functional state of the liver were examined in the intensive care unit, with optimization of correction of hepatic encephalopathy. In addition to traditional therapy, hepatoprotections and drugs that stop transaminase activity are included in patients. Conclusions: Early detection of hepatic encephalopathy before clinical manifestations and timely correction is pathogenetically justified and optimizes the outcomes of such a formidable complication as hepatic encephalopathy and coma. KEYWORDS Liver, liver failure, hepatic encephalopathy, endotoxicosis, endotoxemia, intoxication, diabetes mellitus. Volume 05 Issue 11-2023 20 The American Journal of Medical Sciences and Pharmaceutical Research (ISSN – 2689-1026) VOLUME 05 ISSUE 11 Pages: 20-29 SJIF IMPACT FACTOR (2020: 5. 286) (2021: 5. 64) (2022: 6. 319) (2023: 7. 396) OCLC – 1121105510 Publisher: The USA Journals