Взаимосвязь поражений почек и метаболического синдрома у больных подагрой

Аннотация

The 49 patients was examinationed (mean age - 50.6 ± 1.6 years, duration of the disease - 9.4 ±1.7 years), male and gout showed clinical and laboratory signs of kidney damage in 65.3%, chronic renal failure - in 49.0% of patients. Kidney damage and signs of CKD were more commonly detected in patients with older age, with a large number of affected joints, tophi, frequent exacerbations of the articular syndrome and increased severity of gout. Clinical forms of metabolic syndrome (MS): 1 and 11 degrees of obesity were diagnosed in 30.6%, arterial hypertension in 26.5%, and type 2 diabetes in 12.2% of patients. The presence of MS contributes to the deterioration of the kidneys. The degree of increase in total lipids and cholesterol in serum is accompanied by a decrease in GFR (r = -0.50; r = -0.40).