Экспериментальное обоснование эффективной терапевтической дозы альбендазола для профилактики рецидива эхинококкоза

Аннотация

To study the effect of albendazole in various dosages on the formation of the echinococcal cyst (bladder), experiments were conducted on sheep (8 sheep) artificially infected with echinococcosis. To determine the ef-fect of albendazole, liver tissues of sheep subjected to and not subjected to chemotherapy were studied. A com-parative study of the emerging embryonic blisters of sheep treated and not treated with albendazole showed a significant difference in the dynamics of the formation of embryonic blisters. Albendazole in a dose of 5 mg / kg of weight affects the fatal effect on the embryonic form of echinococcus and is an effective therapeutic dose without toxic effect in the prevention of relapse of echinococcosis