Клинико-иммунологические аспекты психофармакотерапии алкоголизма

Аннотация

The Article studies the dynamics of immunological changes and correlated psychopharmacothcrapy of patients with alcoholism. Clinical immunological method examined 50 male patients with alcoholism at the age of 40-60 years, which determined the activity of autoantibodies to brain and liver cells. During the period of acute intoxication, serum autoantibody concentration was within of 6,5±1,6 ng/ml. And after the combined treatment, autoantibodies fell to 2,1 ±0,7 ng/ml, that is more than 3 times lower. The effect of psychotropic medications on clinical and immunological processes was studied and revealed immunomodulating effect of tranquilizers and atypical neuroleptics.