ASSESSING THE EFFICACY OF ANTIVIRAL DRUGS AGAINST FELINE IMMUNODEFICIENCY VIRUS

Аннотация

Feline Immunodeficiency Virus (FIV) is a lentivirus that infects domestic cats and other feline species, leading to an immunodeficiency syndrome similar to human immunodeficiency virus (HIV) infection in humans. The management and treatment of FIV are essential to improve the quality of life and longevity of infected cats. Antiviral drugs have been investigated as potential treatment options for FIV, aiming to inhibit viral replication and disease progression. This study aims to assess the efficacy of antiviral drugs against FIV through in vitro and in vivo experiments. In vitro studies involved testing the antiviral activity of various drugs against FIV-infected feline cell cultures. In vivo evaluations were performed using FIV-infected cats, administering the selected antiviral drugs and monitoring viral load, clinical symptoms, and immunological parameters. The results offer critical insights into the effectiveness of different antiviral drugs and their potential for managing FIV in domestic cats. KEYWORDS Feline Immunodeficiency Virus, FIV, antiviral drugs, lentivirus, HIV, in vitro, in vivo, viral replication, disease progression, treatment options, infected cats, feline cell cultures, viral load, clinical symptoms, immunological parameters, domestic cats.