Влияние трипсина на иммунные характеристики и протеолитическую активность спермы у мужчин с нарушением фертильности

Аннотация

In men with unpaired tenuity, proteolytic and anti-proteolytic activity was studied in the ejaculate, as well as the rates of pro- and anti-inflammatory interleukins after their treatment with trypsin. In men with impaired fertility, there is a decrease in total proteolytic activity and an increase in the antiproteolytic activity of sperm. The increase in antiproteolytic activity is more associated with the local and systemic reaction to the inflammatory process, but to a lesser extent with the inhibition of sperm proteases. After treatment with trypsin in men with impaired fertility, there was a decrease in antiproteolytic and an increase in the proteolytic activity of sperm. The use of trypsin as an immunocorrective factor of male sperm helps to improve its immune characteristics.