HYPOLIPIDEMIC EFFECT OF ETHANOLIC SEED EXTRACT OF BACCAUREA RAMIFLORA IN WISTER ALBINO RATS

Аннотация

The present study investigated the hypolipidemic effect of the ethanolic seed extract of Baccaurea ramiflora in Wister albino rats. Hyperlipidemia is a major risk factor for cardiovascular diseases, and natural plant extracts have gained attention as potential therapeutic agents for managing lipid disorders. In this study, Wister albino rats were orally administered with different doses of the ethanolic seed extract for a specified duration. The lipid profile, including total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), was measured to assess the hypolipidemic effect of the extract. The results demonstrated that the ethanolic seed extract of Baccaurea ramiflora significantly reduced total cholesterol, triglycerides, and LDL-C levels, while increasing HDL-C levels in hyperlipidemic rats. These findings suggest a potential hypolipidemic effect of the extract, indicating its potential use as a natural therapeutic agent for managing dyslipidemia and reducing the risk of cardiovascular diseases. KEYWORDS Baccaurea ramiflora, ethanolic seed extract, hypolipidemic effect, hyperlipidemia, lipid profile, Wister albino rats.