ИЗУЧЕНИЕ ЭФФЕКТИВНОСТИ ПРОТИВОВИРУСНЫХ ПРЕПАРАТОВ ПРЯМОГО ДЕЙСТВИЯ ПРИ ЛЕЧЕНИИ ХРОНИЧЕСКОГО ВИРУСНОГО ГЕПАТИТА С

Аннотация

Epidemiological features of patients with HCV infection who were under dispensary observation in polyclinics of the Bukhara region were studied, the number of patients was 125, of which 87 (69.6%) were women and 38 (30.4%) were men. Epidemiological diagnosis of HCV was performed by detecting the RNA and genotype of HCV virus infection in blood scrum by polymerase chain reaction (PCR) in real time. The first genotype of the virus was detected in 87.2% (n=109) patients, 0.8% (n=l) the second, and 12% (n l 5) the third. Complete elimination of viruses in 98.4% of cases was achieved using a combination of sofosbuvir and Daclatasvir, directly from antiviral drugs.