Общая характеристика медицинских свойств материала колетэкс-адл

Аннотация

tis of odontogenic origin: A case series // J. Clin. Exp. Перевязочные материалы являются важной ча- Dent. – 2017. – Vol. 9, №1. – P. e150-e152. стью процесса лечения. В последнее время хими- 12. Filiaci F., Riccardi E., Mitro V. et al. Disseminated ne- ческие текстильщики вместе с биологами и врача- crotic mediastinitis spread from odontogenic abscess: ми придают особое значение приданию туалетным our experience // Ann. Stomatol. (Roma). – 2015. – Vol. материалам дополнительного медицинского эф- 6, №2. – P. 64-68. фекта с добавлением к ним лекарств. 13. Guzmán-Letelier M., Crisosto-Jara C., Diaz-Ricouz Ключевые слова: воспалительные заболевания C. et al.. Severe odontogenic infection: An emergency. и травмы челюстно-лицевой области, перевязоч- Case report // J. Clin. Exp. Dent. – 2017. – Vol. 9, №2. ные материалы, инновационные технологии. – P. e319-e324 14. Lewandowski B., Pakla P., Wołek W. et al. A fatal case As we know, textiles in medicine are traditionally of descending necrotizing mediastinitis as a complica- used for the manufacture of dressings. Napkins, ban- tion of odontogenic infection. A case report // Kardio- dages and other various materials have always been chir. Torakochirurgia Pol. – 2014. – Vol. 11, №3. – Р. and remain to be used, since already without them no 324-328. operation can be performed. Their effectiveness lies 15. Precious D.S., Lung K.E., Pynn B.R., Goodday R.H. in such qualities as: high sorbed ability, breathability, Presence of impacted teeth as a determining factor of elasticity, ease of use, and others. unfavorable splits in 1256 sagittal-split osteotomies // Dressings are also an important part of the treat- Oral Surg. Oral Med. Oral Pathol. Oral Radiol. En- ment process. They serve to drain wound surfaces dod. – 1998. – Vol. 85, №4. – P. 362-365. and protect them from secondary infection. Varieties of dressing facilities are currently quite wide, which meet modern methods of treatment of wounds. The creation of these tools is the result of the constant search for new dressing tools that contribute to the rapid healing of wound surfaces. Recently, chemical textile workers, together with biologists and physicians, have attached particular importance to giving dressing materials an additional 19 STOMATOLOGIYA medical effect with the addition of drugs to them. By It is known that Coletex-ADL contains active in- studying such a problem, the materials will not only gredients like: sodium alginate, dioxidine and lido- close the wound from infection and absorb blood, but caine. Sodium alginate was chosen as a biopolymer will also have a healing effect due to the injected drug. for polyfunctional PS Coletex-ADL. According to the In this case, the drug added to the material should results of research by many authors, sodium alginate, have a prolonged-action effect. At the same time, the which contains a large number of trace elements, is a dose and effect of the drug must comply with medical prodrug. Necrosis of tissues does not occur under the standards. In the event that if the dressing with the alginic layer, and under alginate dressings, the period added drug has a prolonged effect, then there will be of necrolysis of non-viable tissues is shortened, which no need for frequent dressings, and the wound healing favorably affects the course of the wound process. process will not be disturbed. There are very differ- Alginates, as mentioned above, stimulate phagocy- ent ways of introducing drugs and biologically active tosis, where phagocytes are the main “orderlies” in substances into the textile material, and it also has the body. Alginates attract to themselves (sorb) and its own, special requirements for all drugs in terms thus make inactive circulating immune complexes of suitability and on the side of their acceptability in in the blood. The immune complex is a conglomer- practice. First, the textile material must be non-tox- ate consisting of an antigen (the protein portion of ic, atraumatic, secondly, it should not crumble into the microbial wall, a foreign substance) and a spe- the wound and not stick to the wound, injuring the cific protein produced by the immune system – the damaged surface, and also it must have a certain vis- immunoglobulin (also called an antibody). If there are cosity and have an additional therapeutic effect de- an excessive amount of such immune complexes in pending on the added drug. Taking into account the the blood, the body does not have time to clear them. above requirements, sodium and calcium alginate and Excessive amounts of circulating immune complexes the sodium salt were chosen as the polymer base. The damage the vascular wall of the smallest blood ves- preference of alginates is due to the fact that they sels in almost all organs and cause an inflammatory have a pronounced hemostatic effect, anti-inflamma- reaction. The damaging role of excess circulating im- tory and reparative properties. Sodium salt of alginic mune complexes has be