Механизм лечебного эффекта лазерной терапии и крема чистотел у больных ангеитом кожи и препарата лефно у больных артропатической формой псориаза к IgE

Аннотация

В статье изучены эффективность лазерной терапии у пациентов с артропатической формой псориаза и анггитов кожи основанных на изменениях иммунологических параметров. Было обследовано 50 пациентов. Из них 25 пациентов с ангиитами кожи (10 - мужчин и 15 - женщин), 25 пациентов с артропатической формой псориаза (12 - мужчин и 13 - женщин). Была использована лазерная терапия, которая дала положительный эффект у всех пациентов. Во время лечения показания IgE были приведены в норму. Ключевые слова: лазеротерапия, ангииты кожи, артропатическая форма псориаза, эффективность лазеротерапии, IgE (immunoglobulin - E). Adhamjon Begishevich PAKIRDINOV Kakhramonjon Nazhmidinovich KHAITOV Andijan State Medical Institute Tashkent Pediatric Medical Institute. Department of dermatology and venereology THE MECHANISM OF THERAPEUTICAL EFFECT OF LASER THERAPY AND CREAM CHISTOTEL AT THE PATIENTS WITH THE SKIN ANGEITIS AND PREPARATION LEFNO AT THE PATIENTS WITH THE ARTHROPATIC FORM OF PSORIASIS TO THE IgE. 105 БИОМЕДИЦИНА ВА АМАЛИЁТ ЖУРНАЛИ | ЖУРНАЛ БИОМЕДИЦИНЫ И ПРАКТИКИ | JOURNAL OF BIOMEDICINE AND PRACTICE №3 | 2021 ANNOTATION The aim of work was to study the effectiveness of laser therapy in patients with arthropatic form of psoriasis and angiitis of the skin based on changes of immunological parameters. Forty-five patients were observed. There 25 patients with angiitis (10 males and 15 females), 25 patients with arthropathic form of psoriasis (12 males and 13 females). In combined use of laser therapy positive changes were revealed in all the patients. During the treatment concentration of IgE was reduced to normal limits. Keywords: laser therapy, skin angiitis, arthropathic form of psoriasis, low level laser therapy, IgE (immunoglobulin – E). Адхамжон Бегишевич ПАКИРДИНОВ Кахрамонжон Нажмидинович ХАИТОВ Дерматовенерология кафедраси Андижон Давлат тиббиёт институти Болалар тери ва таносил касалликлар кафедраси Тошкент Педиатрия медицина институти ТЕРИ АНГИИТИ БИЛАН ОҒРИГАН БЕМОРЛАРИГА ЛАЗЕРОТЕРАПИЯ ВА КРЕМ ЧИСТОТЕЛНИ ҲАМДА ЛЕФНО ПРЕПАРАТИНИ АРТРОПАТИК ПСОРИАЗЛИ БЕМОРЛАРИ IgE КЎРСАТКИЧЛАРИГА ТЕРАПЕВТИК ТАЪСИРИ МЕХАНИЗМИ АННОТАЦИЯ Ишнинг мақсади иммун статуснинг айрим параметрларидаги ўзгаришлари хисобга олган ҳолда тери ангиити ва артропатик псориаз билан оғриған беморларда лазер терапия самарадорлигини ўрганишдан иборат. Қузатувимизда 50 бемор бўлиб, улардан 25 тасида (10 та эркак ва 15 та аёл) тери ангиити, 25 тасида (12 эркак ва 13 та аёл) артропатик псориази аниқланган. Лазер терапия қўлаш натижасида уларнинг барчасида ижобий ўзгариш, шунинг билан бирга иммун тизим томонидан қонзардобидан концентрациясининг меъёрий қўрсатқичларга пасайиши қузатилди. Қалит сўзлар: лазер билан даволаш, тери ангиити, артропатик псориаз, лазертерапиядан эффект, IgE (иммунглобулин - Е). Urgency. The problem of treatment of autoimmune dermatosesis enough actual, that is connected with a significant spread and severe course of dermatosis. Particularly well developed, drug therapies, as the drugs are not always effective and sometimes is associated with the appointment of various side effects and complications, sometimes very heavy [1, 2, 3, 4, 5, 6]. One of these effects is the laser therapy Milta-F-8-01 (Figure1). Laser therapy is still widely introduced into clinical practice, since it is a relatively safe and quite effective method of treatment. In recent years, the use of laser therapy for therapeutic purposes is increasingly used in many disease states. The main objective of laser therapy is a modulation of adrenergic and cholinergic mechanisms of regulation of metabolic and energy processes [7, 8, 9, 10, 11, 12, 13, 14, 15]. Figure 1: Milta-F-8-01 The purpose of research - is the study of the mechanism of laser therapy, therapeutic effect on immunologic parameters in patients with vasculitis of the skin and psoriasis Arthropathic. Materials and methods. The aim of this work is to study the effectiveness of laser therapy using gel Celandine patients skin vasculitis and Lefno the drug in 106 БИОМЕДИЦИНА ВА АМАЛИЁТ ЖУРНАЛИ | ЖУРНАЛ БИОМЕДИЦИНЫ И ПРАКТИКИ | JOURNAL OF BIOMEDICINE AND PRACTICE №3 | 2021 patients with psoriasis Arthropathic considering the changes in some parameters of the immune system. The study included 50 patients. Of these skin vasculitis suffered 25 patients (10 - men and 15 - women, aged 20 to 50 years), Arthropathic psoriasis - in 25 patients (12 - men and 13 - women, aged 19 to 45 years). Diseases of different lesions, long and persistent course, resistant to prior therapy, including several patients to corticosteroids, cytostatics. Patients with skin angiitis (table number 1, picture number 2) and Arthropathic forms of psoriasis (table number 1, number 2) has been selected laser therapy mode. Table №1 Modes irradiation treatment zones in the treatment of skin angiitis Radiationarea Terminal Frequency Power LED Nozzle Exposition, Hz minutes smW (laser, W) The skin, the КТЗ-4 1500-5000 50 № 7/МN 4-10 affected area Epigastric