ДИНАМИКА ИЗМЕНЕНИЙ ПОКАЗАТЕЛЕЙ АНТИОКСИДАНТНОЙ СИСТЕМЫ В СЛЮНЕ У ДЕТЕЙ ПОСЛЕ УРАНОПЛАСТИКИ С ПРИМЕНЕНИЕМ АКТОВЕГИНА

Аннотация

1. Бессонов С.Н., Давыдов Б.Н. Стандартыком- плексного Предложен способ формирования моделей травмати- лечения пациентов с деформациями средней зоны лица, ческого неврита на экспериментальной модели острой травмы обусловленными врожденными расщелинами верхней губы и нижнего альвеолярного нерва. Авторы проанализировали неба II Стандартизация методов лечения в пластической и ультраструктурные изменения в нервном волокне на третий, реконструктивной хирургии: Материалы 2-й Всеукраинской десятый и тридцатый день. На третий день после травмы мы науч.-практ. конф. - Киев, 2006.-С. 8-9. наблюдали нарушение внутрисистемной гемомикроциркуляции, 2. Борисов Г.А., ПенкновичА.А., Мухина И.В. Мета- вызванное повышенной проницаемостью сосудов. К 10-му дню болические эффекты нейротропного действия актовегина в эксперимента в периневральной ткани и самом нервном волокне условиях гипоксии 1/Экспер. и клин, фармакол. -1 999.-NS2.- преобладали дегенеративные и воспалительные процессы. На C.61-63. 30-е сутки после повреждения сосудистонервного пучка нижнего 3. ГерасимоваЛ.Л. Сравнительный анализ эффек- альвеолярного нерва дегенеративные и воспалительные тивности различных методов комплексной терапии детей с явления в нервном волокне сменились дегенеративными и врожденными расщелинами верхней губы и неба: Автореф. склеротическими процессами. дис.... канд. мед. наук. - Пермь, 1991.—21 с. 4. Дьякова С.В., Яковлев С.В., Першина М.А. Современный Annotation подход к диспансеризации детей с врожденной патологией We propose a method of forming models of traumatic neuritis in челюстно-лицевой области IIВрожденная и наследственная an experimental model of acute trauma of the inferior alveolar nerve. патология головы, лица и шеи у детей: актуальные вопросы We analyzed the ultrastructural changes in the nerve fiber on the комплексного лечения: Материалы 2-й Всерос. науч.-практ. third, tenth, and thirtieth day. On the third day after the injury, we конф. - М., 2006. - С. 85-89. observed a violation of the 30 Стоматология • №2(75)2019 ■ eastern hemomicrocirculation caused by increased vascular glutaraldehyde solution on phosphate buffer with a pH of 7.4, 3 jevmeability. By the 10th day of the experiment, in the :e- neural followed by fixation by Millohing one percent solution of OsO4. After tissue and the nerve fiber itself, degenerative and -■ammatory dehydration in acetone, the nerve pieces were poured into epon and processes dominated. On the 30th day after the *>-7 of the placed in a thermostat at + 60° C for 48 hours to polymerize the neurovascular bundle of the inferior alveolar -e-.e. degenerative and resin. UMTP-7 ultramicrotome was used to obtain semi-thin J inflammatory phenomena in the -=-.e fiber gave place to sections, on the basis of which targeted sharpening of the pyramids j degenerative and sclerotic :neoesses. was carried out. Ultrathin sections were stained with uranyl acetate Key words: Ultrastructural changes in the nerve fiber, and lead citrate by Reynolds, viewed and photographed in a I/ Ecenmental model, Traumatic neuritis, Inferior alveolar transmission electron microscope PEM-100. Results and discussion The developed methodology of the experiment stimulates "'acmatic neuritis (TN) of the inferior alveolar, nerve in the : situations that arise during the short-term penetration of the dental 3 .“scent dental practice is one of the most frequent complica- № implant into the mandibular canal, removal of the lower molars 1 arising from non-compliance with the technique :;-?_ction (including retained and dystopic third molars) directly adjacent to the . anesthesia, endodontic treatment of molars and «rrfcular premolars, inferior alveolar nerve. dental implants, removal of third lower ■ ■ (especially regarding When observing the animals of this series in the 1st day after retention and dystopia). surgery there was swelling and hyperemia of soft tissues around the :'otlems of damage and regeneration of the nervous sue and operating wound that spread to neighboring areas. Animals were pathological changes in the nerve fiber during re.srrent were lethargic, poorly consumed food. By the 3rd day tissue edema discussed in many scientific publications sarachev DA, Chumakov slightly decreased, hyperemia persisted and slight infiltration E.I., 1999; Timofeev A., Vesova 2906: Popelyansky J.Yu., 2005; appeared around the edges of the wound. Palpation of tissue in the Edranov S.S., 2008). At re same time, most of the works describes wound area caused a violent motor reaction of animals. By the 10th the morphological re - ces that occur with the complete crossing of and 30th day on the mucous membrane of vestibule of the mouth the nerve. was determined dense whitish scar, slightly towering over S jгificantly less research were devoted to injuries accom- :&■ surrounding tissues. Palpation of tissues in the scar area in animals ec oy short-term mild damage to the inferior alveolar ner- e = r cugh caused a moderate motor response. such dam