ПАТОГЕНЕТИЧЕСКОЕ ЗНАЧЕНИЕ ПОЛИМОРФНЫХ ГЕНОВ МАТРИКСНЫХ МЕТАЛЛОПРОТЕИНАЗ И ИХ ТКАНЕВЫХ ИНГИБИТОРОВ В РАЗВИТИИ ХРОНИЧЕСКОГО ГЛОМЕРУЛОНЕФРИТА У ДЕТЕЙ

Аннотация

The incidence of chronic glomerulonephritis has been steadily progressing over the past 10 years and accounts for 36.76% of all diseases of the kidneys Diseases of the urinary system, according to WHO, currently occupy the 2nd place among the main forms of renal pathology characteristic of childhood. In the structure of kidney diseases in children hospitalized in the nephrological department, glomerulonephritis occupies the second place [I]. The urgency of the problem of chronic glomerulonephritis is explained not by the prevalence of the disease, but by the course of the disease and the development of renal failure [2J. Chronic glomerulonephritis is one of the severe kidney diseases in children, which is characterized by the frequent development of complications and progression of the disease.