IMPROVING THE TREATMENT OF CHRONIC RECURRENT AFTHOUS STOMATITIS

Аннотация

Percentage of human population that suffer from chronic inflammatory parodontal diseases amounts to 70-98% [1]. This group of diseases is considered to be one of the most common reasons of teeth loss among people over 40 years of age. There are more than 50 somatic pathologies known to date, that get compounded by damage of parodontal tissues with 100% probability [2]. There is a tendency for «rejuvenation» of parodontal inflammatory diseases, that results in increasing prevalence among the age group of 18-24 [3]. Another tendency is that aggressiveness and severity of diagnosed pathologies increases considerably [4]. Statistically significant prevalence of vitamin D (21-29 ng/ml or 52,5-72,5 nmol/l) and deficiency (11-20 ng/ml or 27,5-50 nmol/l) [5], laboratory data in an array of research enable us to claim a substantial reverse dependence of parodontal inflammatory diseases’ intensity on vitamin D levels. Термином «витамин D» объединяют группу сходных по химическому строению форм жирорастворимого витамина D (D1- D7), наибольшая роль принадлежит метаболитам D 2 - эргокальциферола- и D 3 - холекальциферола кальцидиолу 25(OH)D и кальцитриолу - 1,25(OH)2D. Рецепторы к витамину D 52