Evaluation of the sensitivity of microflora of the periodontal pocket to antibacterial agents in the conditions of the rural population

Аннотация

Relevance of the topic: the use of antibiotics after surgery in the treatment of periodontal disease is aimed at eliminating the pathogenic microflora of the periodontium, oral cavity and restoring the normal microbiota, which is inherent in healthy periodontal tissues. We know that periodontal diseases are caused by periodontal pathogens: Porphyromonas gingivalis. Actinobacillus actinomycetemcommitans ,Bacteroides forsithus, Threponema denticola , Prevotella intermedia, Actinomices viscosus. Numerous studies suggest that the role of polymicrobial synergy in the development of dental diseases. When prescribing antibacterial drugs, the doctor should remember that most microorganisms of the oral cavity are combined into a microbial biofilm. Microorganisms of the oral cavity form a microbial biofilm on the surface of the teeth – a special form of organization of microorganisms, which is surrounded by a protective matrix – a complex of glycosaminoglycans and proteins. It is this protective matrix that does not allow antibacterial drugs from saliva or gingival fluid to penetrate inside the biofilm. Therefore, microorganisms in the biofilm are more resistant to antibiotics, antimicrobials and other active agents. The most effective choice for the treatment of infectious and inflammatory processes of the oral cavity should be based on the results of modern scientific research, proving the clinical and microbiological efficacy and safety of any drugs.