ANALYSIS OF TORASEMIDE BY CHROMATOSPECTROPHOTOMETRIC METHOD

Аннотация

Torasemide is a loop diuretic. When used in low doses, its diuresis rate is similar to that of the thiazide group, and the maximum effect is achieved 2 hours after administration. The drug is rapidly and almost completely absorbed into the blood. In patients with impaired liver function, an increase in the concentration of torasemide in the blood plasma is observed. Therefore, such patients should exercise caution. The toxic effect of torasemide can lead to serious complications such as arterial hypotension, confusion, thrombosis, cardiac arrhythmias, angina pectoris and acute myocardial infarction as a result of impaired water and electrolyte balance, increased metabolic alkalosis and excessive diuresis. From the urinary system. In patients with impaired urinary excretion, it can lead to rapid urine output, its retention and overdistension of the bladder. Sometimes the level of uric acid, glucose, lipids in the blood increases.