EVALUATION OF HYPOLIPIDEMIC ACTIVITY OF FLAVONOIDS FROM CROCUS SATIVUS

Аннотация

It is currently established that lipid metabolism disorders are a leading risk factor for the development of cardiovascular diseases -vascular diseases, mainly due to the significant influence of cholesterol on the development of atherosclerosis, diabetes mellitus, obesity, and, accordingly, the risk of developing ischemic stroke. Therefore, the search for new active agents capable of exerting a pharmacocorrective effect on impaired lipid metabolism remains a highly relevant task. As part of the ongoing search for new non-toxic and effective herbal remedies for the treatment of cardiovascular disease and ischemic stroke, encouraging results were obtained when considering a drug with the tentative name “Saflavin” (dry powder of the aqueous fraction of the ethanol extract of secondary metabolites of Crocus sativus L. stamens).