HISTOLOGICAL REMODELING OF THE THYMUS UNDER STRESS-INDUCED SECONDARY IMMUNODEFICIENCY

Аннотация

The increasing prevalence of psychosocial stressors, malnutrition, and environmental factors has significantly contributed to the development of secondary immunodeficiency worldwide. The thymus, as the central organ of T-lymphocyte maturation, is one of the most stress-sensitive structures. Understanding thymic morphological damage under stress is crucial for early diagnosis, prevention, and development of therapeutic strategies in clinical immunology and pathomorphology.