DEVELOPMENT AND STANDARDIZATION OF SYNBIOTICS WITH LACTOBACTERIUM PLANTARUM SUBSTANCE AND OLIGOSACCHARIDES

Аннотация

According to the definition by the World Health Organization (WHO), probiotics are viable microorganisms that, when administered in adequate amounts, confer a health benefit on the host. In 2013, the International Scientific Association for Probiotics and Prebiotics refined this definition, stating that the term «probiotic» may only be applied to preparations that meet the following requirements: accurate information on the microorganisms present, including their strains, is provided; a sufficient number of viable bacteria is maintained until the end of the shelf life; and studies confirming the safety and efficacy of the introduced strains are available. Thus, fermented food products and fecal transplants that do not specify species and strain composition are not considered probiotics. Experimental studies and numerous clinical observations have shown that different probiotic strains are necessary for the correction of intestinal symptoms.