Evaluation of Risk Factors of Progressing IgA Nephropathy in Children

Аннотация

Clinical and morphological changes in the IgA nephropathy in children to determine high risk patients for disease progression. Our research included 29 patients at age 80% glomeruli with mesangial proliferation. In our research in children with IgA nephropathy 24 hour protein excretion and frequency of glomeruli with crescents were independent risk factors of permanent proteinuria by the end of 2 years combined therapy. Combined therapy of children with severe IgA nephropathy showed good efficiency, but it can be less effective for children with 24 hour urine excretion >1,32g/1,73m2 or crescents in the biopsy in more than 14% glomeruli.