High Resolution NMR

Аннотация

The preface to the first edition of this book begins with the statement: "Few techniques involving sophisticated instrumentation have made so rapid an impact on chemistry as has nuclear magnetic resonance." I went on to say that "dramatic instrumental developments have improved resolution and sensitivity by factors ^ 5 0 from the first commercial instruments. Today more than 1500 NMR spectrometers are in use, and the scientific literature abounds in reference to NMR data." That was in 1969! NMR had indeed made remarkable advances, but 30 years later, experimental NMR technology bears almost no resemblance to the then "sophisticated" instruments that were almost exclusively based on slow passage, continuous wave techniques. Fourier transform methods were in their infancy, with utilization severely limited by the use of dedicated computers with 4 - 8 kilobytes (not megabytes) of memory. New conceptual approaches to NMR, together with remarkable advances in materials, computers, electronics, and magnet and probe technology, have brought NMR to its current level, with no indication of an end in sight.