THE RELEVANCE OF THE USE AND RESEARCH OF DRUGS THAT HAVE A POSITIVE EFFECT ON METABOLISM

Аннотация

Generally speaking, drugs that affect an organism's metabolism are those that are broken down by the body's metabolic pathways, which frequently involve liver enzymes such as those in the cytochrome P450 family. These medications' duration of action and excretion may be impacted by a variety of metabolic processes, including oxidation, reduction, hydrolysis, and conjugation. Another important factor is the gut microbiota, where bacteria either directly metabolize medications or have an impact on human metabolic processes. The majority of medications are chemically changed by different body systems to produce molecules that are easier for the body to eliminate. These chemical changes, referred to as biotransformations, mostly take place in the liver. Planning customized pharmacological interventions for patients requires an understanding of the molecular changes that medicines go through during metabolism. This exercise goes on polypharmacy, biotransformations, and drug metabolism.