КРЕАТИН ВО ВРЕМЯ БЕРЕМЕННОСТИ: АНАЛИЗ ЭКСПЕРИМЕНТАЛЬНЫХ И КЛИНИЧЕСКИХ ИСПЫТАНИЙ

Аннотация

The article discuss issues of creatine use safety in pregnant women. Literature search has shown that although the use of creatine during pregnancy in humans is not yet fully understood, long-term use of this agent in adults is considered absolutely safe. Authors discourse about creatine synthesis pathways by the fetus, the mechanisms of transfer through the placental barrier. Considerable attention is paid on evidence of benefit of creatine supplementation during pregnancy for prevention and reduction of oxidative stress, fetoplacental hypoxia arising from various types gestational complications, such as fetal growth restriction, premature birth, and cases of fetal hypoxic conditions.