STUDYING THE MORPHOMETRIC INDICATORS OF THE PANCREAS IN LABORATORY ANIMALS WITH INDUCED HYPERTIRHOSIS.

Аннотация

Thyroid dysfunction is polyetiological and may be associated with developmental anomalies, genetic pathology, T-suppressor deficiency, and inflammatory process in thyroid tissue. The study used 30 rats to study the effects of experimental thyrotoxicosis. The rats were divided into two groups - the group with intact animals and the group with experimental hyperthyroidism. Hyperthyroidism was modeled by administering L-thyroxine in various doses over 14 days. Comparative analysis of the morphometric indicators of pancreatic pancreatic cells in control and experimental rats showed that despite the fact that the total cell volume, cytoplasm volume, and nuclear volume of pancreatic cells in hyperthyroid rats were lower than in the control group animals.