Clinical case of trisomy of chromosome-18 (edwards syndrome)

Аннотация

As with most other chromosomal abnormalities, children with Edwards syndrome have a high risk of infant mortality. More than 60% of children die within the first 3 months; no more than one-third of the total number survive to one year of age. Survivors suffer from various forms of mental retardation, anatomical anomalies of the skeleton and internal organs, and multiple systemic disorders, which in most cases also lead to early death. A relatively favorable prognosis is possible only in the mildly mosaic form of the disease. With proper care, some children with it can live up to 10 years or more. At the same time, they all suffer from serious mental retardation up to imbecility.