Genetic aspects in development of diabetic kidney diseases

Аннотация

The increase in diabetes has led to an increase in the number of chronic complications, including diabetic kidney disease (DKD). High prevalence of DKD is particularly associated with high morbidity and mortality rates due to cardiovascular disease. It is known that genetic factors play an important role in the pathogenesis of diabetic kidney disease and may develop in individuals who are genetically susceptible after exposure to environmental factors. Diabetic kidney disease is probably a complex, polygenic disease. Two main directions were used to identify DKD-related genes: candidate gene analysis and genom analysis.