Combination therapy for allergic rhinitis: search for the optimal solution

Аннотация

Allergic rhinitis is a disease that is based on IgE-mediated inflammation of the nasal mucosa (caused by allergens), characterized by at least two of the following symptoms daily: nasal congestion, nasal discharge (rhinorrhea), sneezing, itching in the nasal cavity. Allergic rhinitis is often combined with other allergic diseases, such as bronchial asthma, allergic conjunctivitis, atopic dermatitis, and certainly is a global medical and social problem. Although allergic rhinitis is a serious, life-threatening disease, nevertheless, its medical and social significance is due to its high prevalence among children, adolescents and adults, especially in combination with acute and chronic sinusitis, otitis media and bronchial asthma.