COMPARATIVE ANALYSIS OF DIGITAL SIGNATURE ALGORITHMS (RSA, ELGAMAL)

Аннотация

The article presents data from the authors' studies concerning the use of medicinal plants for the treatment of dermatoses (psoriasis, eczema) of complex etiology, trichophytosis in humans, sheep and goats. For the first time, phytopreparations developed by the authors using a new technology of vacuum-cryogenic crushing of medicinal plants at -1960C are used for the treatment of skin diseases, while moisture is evaporated from plants without disturbing biologically active components, and all macro- and microelements in plants remain unharmed. The results of treatment of dermatosis are as follows: psoriasis - 31 people, 27 (80-85%) recovered, eczema - 38 people, 25 (75-80%) recovered. The results of treatment of trichophytosis of sheep: 56 heads, 53 (95%) recovered, trichophytosis of calves: 38 heads, 33 (90%) recovered. Keywords: Plants, herbal remedies, eczema, psoriasis, trichophytosis, vacuum cryogenic crushing. Introduction. According to WHO (2021), 2-7% of the world's population suffers from dermatoses, and in the Republic of Uzbekistan, skin diseases affect up to 10-12% of the population. Recommended pharmacological synthetic agents do not always lead to the desired results. Among the medicinal plants of Central Asia, a huge number of plants (about 1700 species I.A. Akopov, 1986) grows in the Republic of Uzbekistan. Since ancient times, such plants as licorice, ak-kurai, Richter's hodgepodge, large celandine, wormwood, common pomegranate, leafless anabasis, common almond, harmala, sage and many others have been widely used in scientific medicine. Almost 40% of medicinal plants are used in pharmacological practice. Even the great Avicenna once said that great celandine cures about 250 diseases. About the importance of medicinal plants, V. Stanifort (1974) wrote: "Despite the significant progress in science and technology, humanity is not less, but more dependent on plants as natural 684 EUROPE AN MULTIDISCIPLINARY JOURNAL OF MODERN SCIENCE resources." S. Peisakhovich (1935) isolated 0.1 g of phytoestrogens similar to the female hormone lutein from 1 kg of mountain onion. Goals and objectives of the study. The aim of the research is to develop a technology for the manufacture of phytopreparations from the local flora and fauna of Uzbekistan and their application in practice in veterinary medicine, as well as in medicine. To achieve the goal, the following tasks were set:  Study of the flora and fauna of Uzbekistan for the development of herbal medicines for veterinary medicine and medicine.  Development and improvement of technology for the manufacture of phytopreparations.  Production of complex preparations based on biologically active substances of plants and animal tissues.  Testing of manufactured new complex drugs for the prevention and treatment of skin and gynecological diseases. It is advisable in the future to expand the development, production of local raw materials for the treatment of dermatoses of complex etiology (psoriasis, eczema, trichophytosis, etc.). Material and research methodology. The employees studied the flora and fauna of Uzbekistan. More than 100 medicinal plants growing in the Samarkand region were selected for analysis. We analyzed the macro-microelement composition using luminescent apparatuses (SamSU and Moscow State University) and spectrophotometers "Saturn-1" and "Saturn-2". More than 40 macro-microelement indicators were revealed. From the extracts of medicinal plants, their decoctions and infusions, ointments, liniments, extracts were made using a new technology using BUF-15, BUF-30, vacuum-cryogenic crushing of medicinal plants in order to manufacture living biologically active components from them. The development of methods for identifying biologically active components of medicinal plants and the technology for the manufacture of phytopreparations is based on the method modified by Izbasarova, 2015. For the manufacture of complex herbal preparations, an extract of the necessary medicinal plants was added to the placenta extract. General spectral analyzes and laboratory studies were carried out in the clinical laboratories of the Samara State Medical University, Samara State University and the vivarium of Samarkand State University of Veterinary Medicine, Livestock and Biotechnologies. The manufactured herbal preparations were tested for toxicity and harmlessness on laboratory 30 white mice, 15 rabbits according to the generally accepted method. After confirming the positive results, the phytopreparations were tested on farm animals, as well as on voluntary human patients with dermatoses of complex etiology (psoriasis, eczema, trichophytosis). The data obtained during the study showed that the percentage of recovery is: 85-90% for humans and 70-75% for animals. Research results. The manufactured new complex preparation was examined for harmlessness, toxicity and carcinogenicity on white laboratory mice, which were observed for 28-30 days. During this period, n