Specific morphofunctional changes of the rat thymus gland under the influence of genetically modified soy

Аннотация

The effect of the genetically modified product causes changes in the cytoarchitectonics of the subcapsular, cortical and medullary layers of the thymus gland, indicating increased immigration of T-lymphocyte precursors into the subcapsular zone, activation of the stages of differentiation of T-lymphocytes in the thymus and intensive em-igration of medullary thymocytes against the background of a certain decrease in the level of destruction in the medullary substance of the organ. A significant disorganization of the cytological profiles of the subcapsular and cortical zones of the thymus gland was found, which indicates a greater vulnerability of these structures compared to the medulla. In all areas of the thymus gland, the structure of the population of lymphoid cells changes most significantly, and in the subcapsular substance it is in an emergency state.