Оpnimization of the diagnosis of chronic endometritis in the genesis of undeveloped pregnancy

Аннотация

In the structure of miscarriage, especially at the early stage of the gestational period, one of the main places is occupied by non-developing pregnancy (NDP). Its frequency over the past decade has increased from 5-15% to 25-45% among all cases of gestation. Chronic endometritis can be a major contributing factor to an increase in pregnan-cy failure. Sclerotic changes in the uterine vessels, decreased blood flow in the spiral and radial arteries, characterize the morphological and functional features of the endometrium, showing its inferiority and failure for adequate implantation / nutrition of the ovum. The purpose of this review is to evaluate the best diagnostic methods for chronic endometrium in non-developing pregnancies. Conclusion: in the current review, we found that modern methods of molecular technologies, combined with morphological diagnostics, are capable of providing more complete answers to questions about the causes of missed pregnancies.