Effect of Antihypoxants on the Energy Metabolism of Mitochondria in Some Rat Organs

Аннотация

In experiments on rats, oxygen consumption parameters were studied under conditions of acute exogenous hypoxia without concomitant hypercapnia after administration of a new ant hypoxic selenium metal complex nQ1983 at a dose of 100 mg / kg peros. The standard energy metabolism in rats was also evaluated against the background of the action of the studied substance. As a means of comparison, the well-known antihypoxant Amtisol in the same dose was used. It was found that the substance nQ1983 significantly reduces the rate of oxygen consumption by animals, which can increase their resistance to acute exogenous hypoxia