Pathophysiological point of view impaired hemostasis in gastroduodenal bleeding of ulcer etiology

Аннотация

119 patients with gastric and duodenal ulcer with complicated bleeding. At the time of admission to the clinic in patients with the first degree of blood loss, the level of platelets was 185±8,0×109/l. In patients of group II, on the first day of bleeding, the content of platelets in the venous blood was 268,13±6,13×109/l with a decrease on the 3rd day to 157±4,5×109/l. By the 7th day, this indicator increased to 245,5±5,7×109/l. In patients of group III, it changed in the fol-lowing way: the number of platelets was 130±3.5×109/l, and on the 3rd day their decrease was noted, but the difference with the initial parameters. On the first day of bleeding, activated partial thromboplastin time was up to 25,4±1,5 sec. with its subsequent increase on the 7th day up to 30,0±2,0 seconds in comparison with the control group