Patients of different ages pathomorphological characteristics of exostosis

Аннотация

Osteochondral exostosis is a benign bone growth defect, usually formed in the epiphyseal growth plate. It is mainly located in the metaphyses of the long bones of the limbs, but with skeletal growth it moves towards the diaphysis, but can also be located at the articular ends of the pelvis, ribs, vertebrae, humerus and humerus. It is the most common disease of the skeleton, accounting for approximately 20% of all major skeletal tumors. Most often occurring in children and adolescents (most often in the second decade of life), the growth of osteochondral exostosis stops during skeletal maturity, but sometimes continues after the growth plate has closed. In 70% of cases, solitary osteochondromas are detected in patients under 30 years of age. Osteochondral exostosis develops from the cortical plate of the metaphysis and its axis is directed away from the nearest joint. Osteochondromatosis (multiple exostotic chondrodysplasia) is a hereditary disease, inherited in an autosomal dominant manner, most often occurring in patients under the age of 20. The tibia is the second most common site for the development of exostosis. It accounts for 15-20% of all diagnosed cases of exostoses.