Main Role Of Morphogenetic Between Fgf-23 And Sklotho In The Development Of Herdic And Vasicular Models In Chronic Key Disease Patients

Аннотация

Diabetes is a major cause of chronic kidney disease (CKD). Poor blood sugar control accelerates the progression of CKD to terminal renal failure. Chronic kidney disease is also an important co-morbidity of diabetes. Impaired renal function further increases the risk of cardiovascular events in diabetic patients and ultimately carries a severe social and economic burden. Altered fibroblast growth factor 23 (FGF-23) and Klotho levels are considered the earliest biochemical abnormality of chronic kidney disease, the mineral and bone disease syndrome. KEYWORDS Cardiovascular disease, chronic kidney disease, fibroblast growth factor-23, Klotho, uremic vasculopathy. The U S A Journals Volume 03 Issue 04-2021 134 The American Journal of Medical Sciences and Pharmaceutical Research IMPACT FACTOR (ISSN – 2689-1026) 2021: 5. 64 Published: April 30, 2021 | Pages: 134-141 Doi: https://doi.org/10.37547/TAJMSPR/Volume03Issue04-18 O CLC - 1121105510