CLINICAL AND ECONOMIC EFFICIENCY OF HARDWARE ILEOVANAL ANASTOMOSIS USING A JOHNSON STAPLE IN SURGICAL TREATMENT OF NON-SPECIFIC ULCERAL COLITIS: A COMPARATIVE ANALYSIS

Аннотация

The paper presents a comparative study of the clinical and economic effectiveness of hardware ileoanal anastomosis performed with a Johnson circular stapler in the surgical treatment of nonspecific ulcerative colitis (UC). The data of 100 patients included in the period 2015-2024 were analyzed: the main group - 35 patients operated on using a stapler , and the comparative group - 65 patients in whom the anastomosis was formed by hand suture. It was shown that the use of the device significantly reduced the duration of the operation (142 ± 5 versus 175 ± 6 min), decreased the volume of intraoperative blood loss (480 ± 20 versus 610 ± 25 ml) and reduced the incidence of postoperative complications (8.6% versus 26.2%; p 0.05). The duration of UC before surgery varied from 2 to 15 years (on average, about 8 years in both groups, p>0.05). Thus, the groups were homogeneous in age, gender and duration ofthedisease history. Diagram1Clinical characteristics ofpatients in themain andcomparativegroups (initialdata) On admission, most patients presented characteristic complaints reflecting the severe course of ulcerative colitis. More than 90% of patients in both groups had frequent diarrhea (more than 6 times a day) with blood in the stool. Abdominal pain of varying intensity was present in approximately 70–77% of patients. Signs of systemic intoxication (fever >37.5 °C) were observed in every fifth patient, indicating an exacerbation and high activity of the inflammatory process. Objective laboratory data confirmed the severity of the condition: all patients had mild to moderate anemia (mean hemoglobin ~110 g/l), increased ESR (~30–35 mm/h), and decreased serum albumin levels (~33 g/l), reflecting chronic inflammation and malnutrition. No statistically significant differences in clinical manifestations and laboratory parameters were found between thegroups (Table2,p>0.05). page2155 INTERNATIONAL JOURNAL OF ARTIFICIAL INTELLIGENCE ISSN:2692-5206,ImpactFactor:12,23 AmericanAcademicpublishers,volume05,issue05,2025 Journal: https://www.academicpublishers.org/journals/index.php/ijai Table 2. Clinical manifestations of the disease and laboratory parameters in patients with UC (beforesurgery) Maingroup Compar