NSAID-PATHOLOGICAL PHYSIOLOGY OF GASTROPATHY IN PATIENTS WITH RHEUMATOLOGICAL DISEASES

Аннотация

One of the most important issues in modern rheumatology is the gastroduodenal side effects associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs), which can lead to severe complications. NSAIDs most commonly have a damaging effect on the stomach and duodenum, a condition termed "NSAID-induced gastropathy" or "NSAID-gastroduodenopathy syndrome." The term "NSAID-gastropathy" was introduced in 1986 to distinguish specific gastric mucosal lesions associated with NSAID use from classic gastroduodenal ulcers.