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DIAGNOSTIC VALUE OF CIRCULATING IMMUNE COMPLEXES AS INDICATORS OF SYSTEMIC INFLAMMATION IN CHILDREN WITH EPIDERMOLYSIS BULLOSA

Iroda Khamraeva (Institute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan, Tashkent) · Tamara Aripova (Institute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan, Tashkent) · Adolat Ismailova (Institute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan, Tashkent)

Академические исследования в современной науке · 126-127 · 2025

Аннотация

Epidermolysis bullosa (EB) is a group of rare, genetically determined skin disorders characterized by extreme fragility of the skin and mucous membranes. Although primarily considered a structural disease, increasing evidence supports the involvement of systemic inflammation in its pathogenesis. Circulating immune complexes (CICs), as immune mediators and markers of chronic inflammation, have not been extensively studied in EB, especially in pediatric patients.

Доказательный фрагмент

«Epidermolysis bullosa (EB) is a group of rare, genetically determined skin disorders characterized by extreme fragility of the skin and mucous membranes.»

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Epidermolysis bullosa (EB) is a group of rare, genetically determined skin disorders characterized by extreme fragility of the skin and mucous membranes. Полный текст публикации CiteX не хранит — доступ к первоисточнику открывается по DOI согласно лицензии издателя и выбранному плану.

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Узбекистан
Ключевые слова
epidermolysis bullosa, circulating immune complexes, pediatric inflammation, humoral immunity, immunopathogenesis
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