INFILTRATIVE-SUPPURATIVE TRICHOPHYTOSIS: CHARACTERISTICS OF PROGRESSION AND TREATMENT METHODS

Аннотация

Infiltrative-suppurative trichophytosis is an infectious disease caused by dermatophytes of the Trichophyton genus, characterized by deep involvement of hair and skin. This article explores the etiology, clinical manifestations, diagnostic methods, and contemporary treatment approaches for the disease. The study utilizes microscopic analysis, cultural examinations, and clinical observations. The findings suggest that early diagnosis and comprehensive treatment of infiltrative-suppurative trichophytosis are critical in preventing severe complications. Preventive measures andstrategies to curb the spread ofdermatophytosis are also addressed. Keywords: infiltrative-suppurative trichophytosis, trichophytosis, dermatophytosis, fungal infections, trichophytosis diagnosis, trichophytosis treatment, trichophytosis prevention, Trichophyton. 1.Introduction Trichophytosis is an infectious disease caused bydermatophytes, affecting theskin, hair, and nails. It is particularly prevalent in rural areas and can be transmitted between humans and animals. Infiltrative-suppurative trichophytosis, primarily caused by Trichophyton verrucosum and Trichophyton mentagrophytes var. gypseum, is distinguished by its severe progression and the need for prolonged treatment. This article highlights the clinical features, diagnostic approaches, and modern treatment methods for thecondition. 2.Research Problem and Relevance Infiltrative-suppurative trichophytosis remains a significant issue in dermatology, particularly among rural populations. In many cases, patients neglect the condition or attempt self-treatment, leading to severe progression and long-term complications. Consequently, early detection and the development of effectivetreatment strategies are ofparamount importance. 3.Research Methodology This study was conducted using clinical observations, microscopic examinations, and laboratory analyses. Theprimary methods included: 99 INTERNATIONAL MULTIDISCIPLINARY JOURNAL FOR RESEARCH & DEVELOPMENT SJIF2019:5.2222020:5.5522021:5.6372022:5.4792023:6.5632024:7,805 eISSN:2394-6334 https://www.ijmrd.in/index.php/imjrd Volume12,issue05(2025) •Microscopic Examination:To identifythe causativefungi oftrichophytosis. •Cultural Examination:To determinethespecific species of dermatophytes. •ClinicalObservations: To evaluate thesymptoms and treatment outcomes. •Serological Tests: Used as an auxiliary toolfor differential diagnosis. . 4.Statistical Data Accurate global statistics on infiltrative-suppurative trichophytosis are limited due to its relatively rare occurrence and predominant reporting in rural areas. However, the following data highlight general trends: 1.Prevalence: • Globally, trichophytosis accounts for 20–30% of fungal infections. The infiltrative-suppurative form constitutes approximately 5–10%ofall trichophytosis cases. • In Uzbekistan, trichophytosis is more common in regions with developed agriculture (e.g., Fergana, Samarkand, and Kashkadarya provinces). The annual incidence is estimated at 10–15 cases per100,000population (data are approximatedue toincomplete registration systems). • Children (aged 5–12 years) and adults engaged in livestock farming are the most affected groups. 2.Transmission Dynamics: • Approximately 70–80% of cases are associated with zoonotic transmission, particularly from cattleand dogs. •Incidenceincreases by30–40%inhumid andwarm climates (summerand autumn months). 3.Treatment Outcomes: •With timelytreatment, completerecovery is observed in 85–90%ofcases. • The likelihood of progression to a chronic form is 5–10%, particularly when treatment is delayed. •Permanent sequelae, such as keloid scars orhair loss, are reported in10–15% ofpatients. 5.Research Results and Discussion 5.1. Clinical ManifestationsIn the early stages, the disease presents with erythematous, swollen, and inflamed lesions on the skin. Damage to hair follicles results in hair breakage, creating a “clipped hair” appearance. Purulent discharge is observed from affected areas, and the disease progressively leads to regional lymphadenopathy. 5.2. DiagnosticsDiagnosis is established through microscopic and cultural examinations. Examination undera Wood’s lamp allowsdifferentiation between microsporia and trichophytosis. 5.3.Treatment MethodsThefollowing approaches are employed in thetreatment oftrichophytosis: 1.SystemicTreatment: 100 INTERNATIONAL MULTIDISCIPLINARY JOURNAL FOR RESEARCH & DEVELOPMENT SJIF2019:5.2222020:5.5522021:5.6372022:5.4792023:6.5632024:7,805 eISSN:2394-6334 https://www.ijmrd.in/index.php/imjrd Volume12,issue05(2025) •Antifungal Agents: Terbinafine, Griseofulvin, Itraconazole. •Antihistamines:Clemastine, Loratadine. •Hepatoprotectors: Essentiale Forte. 2.Topical Treatment: •Amixtureofiodinesolution and ethyl alcohol (1:1), applied twice daily. •Antifungal Ointments: Clotrimazole, Miconazole. •Vitamin Therapy: To strengthen theimmunesystem. 6.Conclusion Infiltrative-suppurative trichophytosis is a severe condition th