PREVENTION OF PATHOLOGICAL BLOOD LOSS IN WOMEN WITH PREMATURE BIRTH

Аннотация

Although global efforts are being made to prevent it, obstetric hemorrhage remains a significant risk to the health and lives of mothers and requires study of more effective prevention and treatment measures. Purpose of the study: to develop the prevention of pathological blood loss in women with premature birth. Materials and methods of research: The study included 111 pregnant women with UPR (main 2 groups) to assess the effect of antiplatelet therapy on the functional state of the endothelium during pregnancy. All pregnant women of group I (n=55) with UPR received the proposed therapy in addition to pregnancy-preserving therapy, group II (comparison) (n=56) pregnant women with UPR received traditional therapy. The results of the analysis showed that the use of the drug Dipyridamole in traditional therapy in pregnant women with UPR helps to improve the functional state of the endothelium. These results are achieved due to the effect of therapy on blood clotting mechanisms and the coagulation cascade, which reduces the risk of thrombosis. Considering that some known risk factors for PC are associated with changes in endothelial function, the use of the drug Dipyridamole has a positive effect in terms of prevention of PC.