EFFECT OF TYPE 2 DIABETES MELLITUS ON THE CEREBRAL VESSELS OF PATIENTS WITH CHRONIC BRAIN ISCHEMIA

Аннотация

Objective: to study the state of cerebral vessels in patients with chronic cerebral ischemia (CCI) on the background of type 2 diabetes mellitus (DM) and without DM. Methods: In a case-control study, 229 patients with stage I-II CCI were included. The diagnosis of CCI and its stage was established in accordance with existing criteria (Schmidt E.V., 1985; International Classification of Diseases 11th revision, 2022). Laboratory studies were performed for all patients, including fasting glucose, glycated serum hemoglobin, lipid spectrum (triglycerides, cholesterol, HDL and LDL), apoA1 and apoB. Results: Type 2 diabetes poses a higher risk of developing extracranial atherosclerotic disease than intracranial atherosclerosis, for the development of which both the duration of diabetes and the degree of its compensation are of no small importance. Conclusions. DM is an important risk factor for the development of cerebral atherosclerosis in patients with CCI. In CCI patients with type 2 diabetes, atherosclerotic changes more often affect extracranial vessels than intracranial ones.