EVALUATION OF THE NATURE OF CHANGES IN CELLULAR AND HUMORAL IMMUNITY DURING CLINICAL FORMS OF NONSPECIFIC ULCERATIVE COLITIS

Аннотация

In the gastroenterological department of the Samarkand City Medical Association, 48 patients with a diagnosis of nonspecific ulcerative colitis were observed. The study examined patients with chronic recurrent, chronic continuous, acute form of NUC. A decrease in the relative number of T-lymphocytes, an increase in the relative and absolute number of B-lymphocytes, the concentration of immunoglobulins of class A, M, G, the number of EKK and functional activity were also revealed. It has been confirmed that the state of the immune system in patients with NUC is directly dependent on the form of the disease, the severity of the course and the activity of the pathological process. In conclusion, it was noted that the determination of the state of the immune system in NUC can serve as a criterion in determining the form and severity of NUC.