RESULTS OF THE EXPERIMENTAL STUDY OF THE ANTI-ADHESIVE PROPERTIES OF THE NEW DOMESTIC "HEMOBEN" DRUG

Аннотация

Many methods have been proposed to prevent adhesion, but the problem has mainly remained unresolved. Currently, there is a number of barrier-type anti-adhesion agents that do not have sufficient effectiveness and have limitations of use. The study assessed the coating effectiveness of the "HEMOBEN" drug in the prevention of the formation of adhesions with surrounding tissues. Experimental studies were performed on white outbred rats of both sexes. The state of the abdominal cavity organs and effusion, the presence and severity of the adhesive process were monitored. The adhesive process was assessed by the number, area and severity of adhesions. An experimental evaluation of the anti-adhesion efficacy of the "HEMOBEN" drug use is characterized by the absence of the development of a pronounced adhesive process with surrounding organs against the background of prolonged fixation to the area of injury of the parenchymal organ. There were no signs of the formation of infiltrates and effusion in the abdominal cavity.