OPTIMIZATION OF TREATMENT OF ACUTE AND RECURRENT RHEUMATIC FEVER IN CHILDREN AND ADOLESCENTS

Аннотация

In order to study the features of the course of acute (ARF) and recurrent (RRF) rheumatic fever in children and adolescents and optimize the treatment of the disease, 52 patients aged 6 to 18 years were examined. The patients were divided into 3 groups: 19 - who received conventional treatment and secondary bicillinoprophylaxis, 15 - who received therapy with the replacement of bicillin-5 with sinurol and 18 - with sinurol and the addition of Ismizhen. All patients underwent appropriate clinical, as well as serological and microbiological examination. The study showed that, despite the ongoing prophylaxis with bicillin-5, microbiological and serological examination gave positive results in many patients. In this connection, the drug was replaced with benzatin-penicillin, in a number of patients with the inclusion of a bacterial stimulant Ismizhen. Patients of 2-3 groups had positive dynamics of clinical indicators, rare subsequent episodes of respiratory infections, microbiological examination of them showed repeatedly negative results. The drug may also be recommended for patients with allergies to penicillin antibiotics.