PATHOLOGANATOMIC FEATURES OF HIALINE MEMBRANE DISEASE IN PREMATURE

Аннотация

This study studied the morphological and morphometric parameters of the disease of the hyaline membrane in premature infants. The material was obtained from the results of clinical and anamnestic analysis of premature infants aged 22–37 weeks and lung tissue. The results show that immaturity of the lung tissue, impaired blood circulation and damage to the alveolar and bronchial epithelium play an important role in the development of the disease of the hyaline membranes in the lungs of premature infants. The results of morphometric studies showed that only 1/3 of the lungs of infants born at the age of 22-27 weeks had air in the alveoli, the thickness of the alveolar interstitial tissue, the alveolar epithelium was relatively large, and the formed hyaline membranes were composed of relatively thin fibers. At 28–32 and 33–37 weeks, the dead groups showed an increase in the area occupied by airborne alveoli in the infant's lungs, thinning of the interstitial tissue and thickening of the hyaline membranes compared with the previous group.