PROSPECTS FOR DIAGNOSING POLYCYSTIC OVARIAN SYNDROME

Аннотация

Multifactorial heterogeneous pathology characterized by chronic anovulation, menstrual irregularities, infertility, cystic ovarian changes and hyperandrogenism is called polycystic ovary syndrome (PCOS). It is approximately 11% among women of fertile age, and in the structure of endocrine infertility it reaches 70%. The aim of the study is to develop modern methods for diagnosing infertility in women with polycystic ovary syndrome based on the study of clinical, anamnestic and laboratory parameters, some genotypic variants of gene polymorphisms, folate metabolism. The cause of chronic anovulation and, as a consequence, infertility in patients with PCOS may be hormonal abnormalities, which were detected in 82% of patients. The most typical for PCOS was an increase in total testosterone - which took place in 63.3% of women, an increase in the LH / FSH ratio of more than 2.5 was noted in 51.3% of patients.