TREATMENT OF CHILDREN WITH VENOUS MALFORMATIONS OF THE LOWER LIMBS

Аннотация

Objective of the study. To improve the effectiveness of treatment in children with isolated and diffuse venous malformations of the lower extremities, as well as in those with Klippel–Trenaunay syndrome. Materials and methods. Over a period of three years, 132 patients aged from 1 to 17 years with various forms and localizations of venous malformations were examined. Of these, 38% had lesions of the lower extremities. Venous malformations of the lower extremities of a nonsyndromic type were diagnosed in 39 patients, and Klippel–Trenaunay syndrome with involvement of the deep venous system was identified in 11 children. In cases of nonsyndromic, localized lesions of the superficial venous system of the lower extremities, treatment was performed using sclerotherapy of the pathological veins with bleomycin and lauromacrogol. On average, 1–6 sessions were conducted; in 3 patients, due to low effectiveness of sclerotherapy, systemic therapy was initiated. Results. Thirty children completed treatment with good outcomes (80% regression) and were placed under dispensary observation, while 6 children continue to receive course-based therapy due to the large volume of the lesions. Conclusions. The effectiveness of treating patients with isolated and diffuse venous malformations of the lower extremities and Klippel–Trenaunay syndrome using sclerotherapy and rapamycin has been confirmed