KIDNEY CONDITION IN CHILDREN WITH EXOGENOUS CONSTITUTIONAL OBESITY

Аннотация

Throughout the world, over the past decades, there has been a steady increase in the rate of childhood obesity. Thus, when assessing the anthropometric data of children in developed countries, it was found that overweight or obesity in developed countries is observed in 28% of schoolchildren and 12% of preschool children [1]. Recently, there is increasing evidence that obesity is an independent risk factor for the development of chronic kidney disease (CKD). Base body mass index (BMI) has been proposed as an independent predictor of CKD progression [2]. Obesity is closely associated with the two most common causes of end-stage renal disease (ESRD), namely arterial hypertension and diabetes mellitus. In addition, metabolic syndrome (MS), as a major consequence of obesity, is also an independent risk factor for ESRD [3]. Recent data also support the hypothesis that reduced insulin sensitivity and hyperinsulinemia are among the most important factors leading to kidney damage [4].